Cigarette smoking significantly alters sperm DNA methylation patterns

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منابع مشابه

Cigarette smoking and DNA methylation

DNA methylation is the most studied epigenetic modification, capable of controlling gene expression in the contexts of normal traits or diseases. It is highly dynamic during early embryogenesis and remains relatively stable throughout life, and such patterns are intricately related to human development. DNA methylation is a quantitative trait determined by a complex interplay of genetic and env...

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Cigarette smoking impairs sperm bioenergetics.

OBJECTIVE The growing consensus on the negative impact of cigarette smoking on fertility prompted us to compare the rate of sperm respiration in smokers and non-smokers. MATERIALS AND METHODS Semen samples from 20 smokers and 58 non-smokers consulting at the andrology laboratory for fertility evaluation were used. Smoking was defined as consumption of at least a half a pack per day. A phospho...

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Adolescent Light Cigarette Smoking Patterns and Adult Cigarette Smoking

PURPOSE Light cigarette smoking has had limited research. The purpose of this study was to examine the relationship between light smoking in adolescence with smoking in adulthood. METHODS National Longitudinal Study of Adolescent Health data, Waves I and IV, were analyzed. Previous month adolescent smoking of 1-5 cigarettes/day (cpd) (light smoking); 6-16 cpd (average smoking); 17 or more cpd...

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Correlation between Sperm Parameters and Sperm DNA Fragmentation in Fertile and Infertile Cigarette Smoking Patients

The present study to investigate that the correlation between sperm parameters and sperm DNA fragmentation in fertile and infertile cigarette smoking patient. Forty men undergoing infertility evaluation were divided into four groups according their smoking ability (A: 2 days ( n=10), B: 4 days ( n=10), C: 8 days ( n=10), D: 15 days ( n=10)) sperm parameters ( sperm concentration, pH, Viscosity,...

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Cigarette smoking patterns during the working day.

The rates at which people smoke cigarettes during different periods of the day were obtained from three occupational groups. Group 1 consisted of those working at the main London production site of a food processing factory, Group 2 consisted of those in the administrative offices of the same company; there are smoking restrictions at both. Group 3 consisted of workers in the offices of a Londo...

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ژورنال

عنوان ژورنال: Andrology

سال: 2017

ISSN: 2047-2919

DOI: 10.1111/andr.12416